GH Secretagogues
Ipamorelin
Pentapeptide secretagogue
Identity
- Class
- GH Secretagogues
- Molecular weight
- 712 Da
- Residues
- 5
- Heavy atoms
- 98
- Reference slug
- ipamorelin
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
A five-residue peptide carrying three non-standard residues: alpha-aminoisobutyric acid at position one, D-2-naphthylalanine at three and D-phenylalanine at four. All three are modelled, and the two D residues have their side chains mirrored so they read as distinct from the L form.
Sequence
BHxfK
This sequence uses notation outside the standard twenty one-letter codes — a lowercase letter marks a D-amino acid, and other symbols mark modified or non-standard residues. It is reproduced exactly as published rather than normalised, and no residue composition is derived from it.
Primary literature
5 peer-reviewed papers indexed in PubMed that name this compound in the title. Each record was checked against the database for title, journal and year rather than written from memory.
The growth hormone secretagogue receptor 1a agonists, anamorelin and ipamorelin, inhibit cisplatin-induced weight loss in ferrets: Anamorelin also exhibits anti-emetic effects via a central mechanism
Physiol Behav2024PMID 39043357
The influence of ghrelin agonist ipamorelin acetate on the hypothalamic-pituitary-testicular axis in a cichlid fish, Oreochromis mossambicus
Anim Reprod Sci2024PMID 38996787
Mechanism of ipamorelin-evoked insulin release from the pancreas of normal and diabetic rats
Neuro Endocrinol Lett2004PMID 15665799
Prospective, randomized, controlled, proof-of-concept study of the Ghrelin mimetic ipamorelin for the management of postoperative ileus in bowel resection patients
Int J Colorectal Dis2014PMID 25331030
Efficacy of ipamorelin, a ghrelin mimetic, on gastric dysmotility in a rodent model of postoperative ileus
J Exp Pharmacol2012PMID 27186127
Citations are listed so the underlying research can be read directly. They describe laboratory and preclinical work on the molecule. They are not evidence of a benefit, and nothing here is an application, dose, route or outcome.
Reference databases
PubChem
Compound record: Ipamorelin
Resolved from the compound name
PubMed
Indexed literature
Live search for Ipamorelin
ClinicalTrials.gov
Registered studies
Live search for Ipamorelin
Links resolved against the live databases on 2026-08-29.
Others in GH Secretagogues
Sermorelin
29 residues · 3358 Da
The first 29 residues of growth hormone releasing hormone, which is the shortest fragment that r…
In our catalogue
Tesamorelin
44 residues · 5136 Da
All 44 residues of human growth-hormone-releasing hormone with a trans-3-hexenoyl group on the N…
In our catalogue
GHRP-2
6 residues · 818 Da
Six residues, three of them D-configuration. Position two is 2-naphthylalanine, the bulky twin-r…
Reference entry
GHRP-6
6 residues · 873 Da
Six residues with D-tryptophan at two and D-phenylalanine at five. Two indole rings sit close to…
Reference entry
Hexarelin
6 residues · 887 Da
Identical to GHRP-6 except for a single methyl group on the indole at position two. That one car…
Reference entry
Mod GRF 1-29
29 residues · 3368 Da
Sermorelin altered at four positions: D-alanine at two, glutamine at eight, alanine at fifteen a…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.