GH Secretagogues
Sermorelin
Human GHRH residues 1 to 29
Identity
- Class
- GH Secretagogues
- Molecular weight
- 3358 Da
- Residues
- 29
- Heavy atoms
- 236
- Reference slug
- sermorelin
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
The first 29 residues of growth hormone releasing hormone, which is the shortest fragment that retains full activity at the receptor. Modelled as an alpha helix.
Sequence
| 1 | YADAIFTNSY RKVLGQLSAR KLLQDIMSR |
|---|
- Three-letter code
- Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-Asp-Ile-Met-Ser-Arg
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Sermorelin is built from 15 of the twenty standard amino acids across 29 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Leucine | L · Leu | 4 | 13.8% |
| Alanine | A · Ala | 3 | 10.3% |
| Arginine | R · Arg | 3 | 10.3% |
| Serine | S · Ser | 3 | 10.3% |
| Aspartic acid | D · Asp | 2 | 6.9% |
| Isoleucine | I · Ile | 2 | 6.9% |
| Lysine | K · Lys | 2 | 6.9% |
| Glutamine | Q · Gln | 2 | 6.9% |
| Tyrosine | Y · Tyr | 2 | 6.9% |
| Phenylalanine | F · Phe | 1 | 3.4% |
| Glycine | G · Gly | 1 | 3.4% |
| Methionine | M · Met | 1 | 3.4% |
| Asparagine | N · Asn | 1 | 3.4% |
| Threonine | T · Thr | 1 | 3.4% |
| Valine | V · Val | 1 | 3.4% |
By side-chain class
Nonpolar, aliphatic
12 · 41.4%
A G I L M V
Aromatic
3 · 10.3%
F Y
Polar, uncharged
7 · 24.1%
N Q S T
Positively charged
5 · 17.2%
K R
Negatively charged
2 · 6.9%
D
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Reference databases
PubChem
Compound record: Sermorelin
Resolved from the compound name
PubMed
Indexed literature
Live search for Sermorelin
ClinicalTrials.gov
Registered studies
Live search for Sermorelin
Links resolved against the live databases on 2026-08-29.
Others in GH Secretagogues
Ipamorelin
5 residues · 712 Da
A five-residue peptide carrying three non-standard residues: alpha-aminoisobutyric acid at posit…
In our catalogue
Tesamorelin
44 residues · 5136 Da
All 44 residues of human growth-hormone-releasing hormone with a trans-3-hexenoyl group on the N…
In our catalogue
GHRP-2
6 residues · 818 Da
Six residues, three of them D-configuration. Position two is 2-naphthylalanine, the bulky twin-r…
Reference entry
GHRP-6
6 residues · 873 Da
Six residues with D-tryptophan at two and D-phenylalanine at five. Two indole rings sit close to…
Reference entry
Hexarelin
6 residues · 887 Da
Identical to GHRP-6 except for a single methyl group on the indole at position two. That one car…
Reference entry
Mod GRF 1-29
29 residues · 3368 Da
Sermorelin altered at four positions: D-alanine at two, glutamine at eight, alanine at fifteen a…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.