Identity
- Class
- Neuropeptides
- Molecular weight
- 2148 Da
- Residues
- 17
- Heavy atoms
- 153
- Reference slug
- dynorphin-a
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Seventeen residues opening with the same tyrosine-glycine-glycine-phenylalanine that every opioid peptide here starts with, then a strongly basic tail of arginines and lysines.
Sequence
| 1 | YGGFLRRIRP KLKWDNQ |
|---|
- Three-letter code
- Tyr-Gly-Gly-Phe-Leu-Arg-Arg-Ile-Arg-Pro-Lys-Leu-Lys-Trp-Asp-Asn-Gln
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Dynorphin A is built from 12 of the twenty standard amino acids across 17 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Arginine | R · Arg | 3 | 17.6% |
| Glycine | G · Gly | 2 | 11.8% |
| Lysine | K · Lys | 2 | 11.8% |
| Leucine | L · Leu | 2 | 11.8% |
| Aspartic acid | D · Asp | 1 | 5.9% |
| Phenylalanine | F · Phe | 1 | 5.9% |
| Isoleucine | I · Ile | 1 | 5.9% |
| Asparagine | N · Asn | 1 | 5.9% |
| Proline | P · Pro | 1 | 5.9% |
| Glutamine | Q · Gln | 1 | 5.9% |
| Tryptophan | W · Trp | 1 | 5.9% |
| Tyrosine | Y · Tyr | 1 | 5.9% |
By side-chain class
Nonpolar, aliphatic
6 · 35.3%
G I L P
Aromatic
3 · 17.6%
F W Y
Polar, uncharged
2 · 11.8%
N Q
Positively charged
5 · 29.4%
K R
Negatively charged
1 · 5.9%
D
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Others in Neuropeptides
DSIP
9 residues · 849 Da
Nine residues with tryptophan at the N-terminus and a run of small residues through the middle.…
In our catalogue
Selank
7 residues · 752 Da
Seven residues, built from the tuftsin fragment with the same proline-glycine-proline extension…
In our catalogue
Semax
7 residues · 814 Da
A seven-residue peptide: the four-residue ACTH fragment with a proline-glycine-proline extension…
In our catalogue
ACTH 4-10
7 residues · 962 Da
Seven residues from the middle of corticotropin. The same fragment that Semax is built on, shown…
Reference entry
Alpha-neoendorphin
10 residues · 1228 Da
Ten residues from the same precursor as the dynorphins, again opening with the shared motif.
Reference entry
Beta-endorphin (1-16)
16 residues · 1746 Da
Sixteen residues from the front of beta-endorphin, beginning with the same four as the enkephali…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.