Neuropeptides
Selank
Tuftsin analogue with a Pro-Gly-Pro tail
Identity
- Class
- Neuropeptides
- Molecular weight
- 752 Da
- Residues
- 7
- Heavy atoms
- 112
- Reference slug
- selank
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Seven residues, built from the tuftsin fragment with the same proline-glycine-proline extension found in Semax. Three prolines in a chain of seven forces an extended backbone.
Sequence
| 1 | TKPRPGP |
|---|
- Three-letter code
- Thr-Lys-Pro-Arg-Pro-Gly-Pro
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Selank is built from 5 of the twenty standard amino acids across 7 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Proline | P · Pro | 3 | 42.9% |
| Glycine | G · Gly | 1 | 14.3% |
| Lysine | K · Lys | 1 | 14.3% |
| Arginine | R · Arg | 1 | 14.3% |
| Threonine | T · Thr | 1 | 14.3% |
By side-chain class
Nonpolar, aliphatic
4 · 57.1%
G P
Polar, uncharged
1 · 14.3%
T
Positively charged
2 · 28.6%
K R
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Primary literature
5 peer-reviewed papers indexed in PubMed that name this compound in the title. Each record was checked against the database for title, journal and year rather than written from memory.
[Comparison of anticoagulant effects of regulatory proline-containing oligopeptides. Specificity of glyprolines, semax, and selank and potential of their practical application]
Izv Akad Nauk Ser Biol2006PMID 16634437
Effect of Selank on Morphological Parameters of Rat Liver in Chronic Foot-Shock Stress
Bull Exp Biol Med2019PMID 31243679
Effect of Selank on Spontaneous Synaptic Activity of Rat Hippocampal CA1 Neurons
Bull Exp Biol Med2017PMID 28361410
Effect of Selank on Functional State of Rat Hepatocytes under Conditions of Restraint Stress
Bull Exp Biol Med2017PMID 28853100
Selank Inhibits Ethanol-Induced Hyperlocomotion and Manifestation of Behavioral Sensitization in DBA/2 Mice
Bull Exp Biol Med2016PMID 27878720
Citations are listed so the underlying research can be read directly. They describe laboratory and preclinical work on the molecule. They are not evidence of a benefit, and nothing here is an application, dose, route or outcome.
Reference databases
PubChem
Compound record: Selank
Resolved from the compound name
PubMed
Indexed literature
Live search for Selank
ClinicalTrials.gov
Registered studies
Live search for Selank
Links resolved against the live databases on 2026-08-29.
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Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.