Metabolic
PepX-3 RT
Triple incretin receptor agonist
Identity
- Class
- Metabolic
- Molecular weight
- 4076 Da
- Residues
- 39
- Heavy atoms
- 289
- Reference slug
- pepx-3-rt
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
A 39-residue lipopeptide studied as a GLP-1 / GIP / glucagon receptor triple agonist. Two positions carry Aib (2 and 20) and one carries alpha-methyl-leucine (13) - all three are modelled. The C20 fatty diacid on Lys17 is a lipid tail and is not drawn, so the mass shown is the peptide backbone only.
Aib at 2 and 20, alpha-methyl-Leu at 13, C20 fatty diacid on Lys17 (tail not shown).
Sequence
YA*QGTFTSDYSIL*LDKK*AQA*AFIEYLLEGGPSSGAPPPS-NH2
This sequence uses notation outside the standard twenty one-letter codes — a lowercase letter marks a D-amino acid, and other symbols mark modified or non-standard residues. It is reproduced exactly as published rather than normalised, and no residue composition is derived from it.
Others in Metabolic
Amylin
37 residues · 3903 Da
Thirty-seven residues with a small disulfide ring at the front. Pramlintide, also in this librar…
Reference entry
Apelin-13
13 residues · 1534 Da
Thirteen residues opening with a pyroglutamate ring, which is drawn. The pyroglutamate form is t…
Reference entry
Apelin-17
17 residues · 2139 Da
Seventeen residues, four longer than apelin-13 at the front and strongly basic there. Both are h…
Reference entry
Exenatide
39 residues · 4187 Da
Thirty-nine residues ending in an amide. Originally isolated from the saliva of the Gila monster…
Reference entry
GLP-1 (7-36)
30 residues · 3298 Da
Thirty residues, the fragment of GLP-1 that is actually active. Every long-acting analogue of it…
Reference entry
GLP-2
33 residues · 3766 Da
Thirty-three residues, cut from the same precursor protein as GLP-1 but acting on the gut lining…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.