Identity
- Class
- Antimicrobial
- Molecular weight
- 1265 Da
- Residues
- 13
- Heavy atoms
- 90
- Reference slug
- alloferon
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Thirteen residues, six of them glycine and four histidine, which makes the backbone unusually flexible. An immune signal rather than a membrane-disrupting peptide, unlike the rest of this group.
Sequence
| 1 | HGVSGHGQHG VHG |
|---|
- Three-letter code
- His-Gly-Val-Ser-Gly-His-Gly-Gln-His-Gly-Val-His-Gly
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Alloferon is built from 5 of the twenty standard amino acids across 13 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Glycine | G · Gly | 5 | 38.5% |
| Histidine | H · His | 4 | 30.8% |
| Valine | V · Val | 2 | 15.4% |
| Glutamine | Q · Gln | 1 | 7.7% |
| Serine | S · Ser | 1 | 7.7% |
By side-chain class
Nonpolar, aliphatic
7 · 53.8%
G V
Polar, uncharged
2 · 15.4%
Q S
Positively charged
4 · 30.8%
H
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Others in Antimicrobial
Aurein 1.2
13 residues · 1480 Da
Thirteen residues forming a short helix with a clear split between its charged and greasy faces.
Reference entry
Bactenecin
12 residues · 1484 Da
Twelve residues with cysteines at three and eleven joined by a disulfide, closing a loop with a…
Reference entry
Beta-defensin 2
41 residues · 4328 Da
Forty-one residues with three disulfides in a different arrangement to the alpha-defensin above.…
Reference entry
Buforin II
21 residues · 2435 Da
Twenty-one residues cut from histone H2A, the protein that packages DNA. A proline in the middle…
Reference entry
Cecropin B
35 residues · 3835 Da
Thirty-five residues in two helices joined by a hinge: a charged one at the front and a hydropho…
Reference entry
Citropin 1.1
16 residues · 1615 Da
Sixteen residues opening with the same glycine-leucine-phenylalanine-aspartate as aurein, which…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.