Identity
- Class
- Antimicrobial
- Molecular weight
- 4328 Da
- Residues
- 41
- Heavy atoms
- 299
- Reference slug
- beta-defensin-2
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Forty-one residues with three disulfides in a different arrangement to the alpha-defensin above. The two families are named for exactly that difference in how their bonds pair up, and both are here to show it.
Sequence
| 1 | GIGDPVTCLK SGAICHPVFC PRRYKQIGTC GLPGTKCCKK P |
|---|
- Three-letter code
- Gly-Ile-Gly-Asp-Pro-Val-Thr-Cys-Leu-Lys-Ser-Gly-Ala-Ile-Cys-His-Pro-Val-Phe-Cys-Pro-Arg-Arg-Tyr-Lys-Gln-Ile-Gly-Thr-Cys-Gly-Leu-Pro-Gly-Thr-Lys-Cys-Cys-Lys-Lys-Pro
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Beta-defensin 2 is built from 16 of the twenty standard amino acids across 41 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Cysteine | C · Cys | 6 | 14.6% |
| Glycine | G · Gly | 6 | 14.6% |
| Lysine | K · Lys | 5 | 12.2% |
| Proline | P · Pro | 5 | 12.2% |
| Isoleucine | I · Ile | 3 | 7.3% |
| Threonine | T · Thr | 3 | 7.3% |
| Leucine | L · Leu | 2 | 4.9% |
| Arginine | R · Arg | 2 | 4.9% |
| Valine | V · Val | 2 | 4.9% |
| Alanine | A · Ala | 1 | 2.4% |
| Aspartic acid | D · Asp | 1 | 2.4% |
| Phenylalanine | F · Phe | 1 | 2.4% |
| Histidine | H · His | 1 | 2.4% |
| Glutamine | Q · Gln | 1 | 2.4% |
| Serine | S · Ser | 1 | 2.4% |
| Tyrosine | Y · Tyr | 1 | 2.4% |
By side-chain class
Nonpolar, aliphatic
19 · 46.3%
A G I L P V
Aromatic
2 · 4.9%
F Y
Polar, uncharged
11 · 26.8%
C Q S T
Positively charged
8 · 19.5%
H K R
Negatively charged
1 · 2.4%
D
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
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This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.