Identity
- Class
- Antimicrobial
- Molecular weight
- 2435 Da
- Residues
- 21
- Heavy atoms
- 172
- Reference slug
- buforin-ii
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Twenty-one residues cut from histone H2A, the protein that packages DNA. A proline in the middle puts a kink in the helix, which is unusual and is thought to matter.
Sequence
| 1 | TRSSRAGLQF PVGRVHRLLR K |
|---|
- Three-letter code
- Thr-Arg-Ser-Ser-Arg-Ala-Gly-Leu-Gln-Phe-Pro-Val-Gly-Arg-Val-His-Arg-Leu-Leu-Arg-Lys
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Buforin II is built from 12 of the twenty standard amino acids across 21 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Arginine | R · Arg | 5 | 23.8% |
| Leucine | L · Leu | 3 | 14.3% |
| Glycine | G · Gly | 2 | 9.5% |
| Serine | S · Ser | 2 | 9.5% |
| Valine | V · Val | 2 | 9.5% |
| Alanine | A · Ala | 1 | 4.8% |
| Phenylalanine | F · Phe | 1 | 4.8% |
| Histidine | H · His | 1 | 4.8% |
| Lysine | K · Lys | 1 | 4.8% |
| Proline | P · Pro | 1 | 4.8% |
| Glutamine | Q · Gln | 1 | 4.8% |
| Threonine | T · Thr | 1 | 4.8% |
By side-chain class
Nonpolar, aliphatic
9 · 42.9%
A G L P V
Aromatic
1 · 4.8%
F
Polar, uncharged
4 · 19%
Q S T
Positively charged
7 · 33.3%
H K R
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Others in Antimicrobial
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35 residues · 3835 Da
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16 residues · 1615 Da
Sixteen residues opening with the same glycine-leucine-phenylalanine-aspartate as aurein, which…
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This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.