Identity
- Class
- Metabolic
- Molecular weight
- 1459 Da
- Residues
- 15
- Heavy atoms
- 98
- Reference slug
- guanylin
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Fifteen residues with two disulfides that cross rather than nest, which is the opposite arrangement to the conotoxins here. Four cysteines out of fifteen residues.
Sequence
| 1 | PGTCEICAYA ACTGC |
|---|
- Three-letter code
- Pro-Gly-Thr-Cys-Glu-Ile-Cys-Ala-Tyr-Ala-Ala-Cys-Thr-Gly-Cys
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Guanylin is built from 8 of the twenty standard amino acids across 15 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Cysteine | C · Cys | 4 | 26.7% |
| Alanine | A · Ala | 3 | 20% |
| Glycine | G · Gly | 2 | 13.3% |
| Threonine | T · Thr | 2 | 13.3% |
| Glutamic acid | E · Glu | 1 | 6.7% |
| Isoleucine | I · Ile | 1 | 6.7% |
| Proline | P · Pro | 1 | 6.7% |
| Tyrosine | Y · Tyr | 1 | 6.7% |
By side-chain class
Nonpolar, aliphatic
7 · 46.7%
A G I P
Aromatic
1 · 6.7%
Y
Polar, uncharged
6 · 40%
C T
Negatively charged
1 · 6.7%
E
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Others in Metabolic
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A 39-residue lipopeptide studied as a GLP-1 / GIP / glucagon receptor triple agonist. Two positi…
In our catalogue
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Thirteen residues opening with a pyroglutamate ring, which is drawn. The pyroglutamate form is t…
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Apelin-17
17 residues · 2139 Da
Seventeen residues, four longer than apelin-13 at the front and strongly basic there. Both are h…
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Thirty-nine residues ending in an amide. Originally isolated from the saliva of the Gila monster…
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GLP-1 (7-36)
30 residues · 3298 Da
Thirty residues, the fragment of GLP-1 that is actually active. Every long-acting analogue of it…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.