Identity
- Class
- Tissue & Structural
- Molecular weight
- 5800 Da
- Residues
- 49
- Heavy atoms
- 411
- Reference slug
- osteocalcin
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
Forty-nine residues, the most abundant non-collagen protein in bone. The natural form carries three modified glutamates that bind calcium; those modifications are not drawn, so this is the unmodified chain.
Sequence
| 1 | YLYQWLGAPV PYPDPLEPRR EVCELNPDCD ELADHIGFQE AYRRFYGPV |
|---|
- Three-letter code
- Tyr-Leu-Tyr-Gln-Trp-Leu-Gly-Ala-Pro-Val-Pro-Tyr-Pro-Asp-Pro-Leu-Glu-Pro-Arg-Arg-Glu-Val-Cys-Glu-Leu-Asn-Pro-Asp-Cys-Asp-Glu-Leu-Ala-Asp-His-Ile-Gly-Phe-Gln-Glu-Ala-Tyr-Arg-Arg-Phe-Tyr-Gly-Pro-Val
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Osteocalcin is built from 16 of the twenty standard amino acids across 49 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Proline | P · Pro | 7 | 14.3% |
| Glutamic acid | E · Glu | 5 | 10.2% |
| Leucine | L · Leu | 5 | 10.2% |
| Tyrosine | Y · Tyr | 5 | 10.2% |
| Aspartic acid | D · Asp | 4 | 8.2% |
| Arginine | R · Arg | 4 | 8.2% |
| Alanine | A · Ala | 3 | 6.1% |
| Glycine | G · Gly | 3 | 6.1% |
| Valine | V · Val | 3 | 6.1% |
| Cysteine | C · Cys | 2 | 4.1% |
| Phenylalanine | F · Phe | 2 | 4.1% |
| Glutamine | Q · Gln | 2 | 4.1% |
| Histidine | H · His | 1 | 2% |
| Isoleucine | I · Ile | 1 | 2% |
| Asparagine | N · Asn | 1 | 2% |
| Tryptophan | W · Trp | 1 | 2% |
By side-chain class
Nonpolar, aliphatic
22 · 44.9%
A G I L P V
Aromatic
8 · 16.3%
F W Y
Polar, uncharged
5 · 10.2%
C N Q
Positively charged
5 · 10.2%
H R
Negatively charged
9 · 18.4%
D E
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
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This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.