TB-500

Identity

Class

Tissue & Structural

Molecular weight

889 Da

Residues

7

Heavy atoms

126

Reference slug

tb-500

These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.

What this compound is

The seven-residue actin-binding stretch of thymosin beta-4, N-terminally acetylated. Studied alongside BPC-157 in tissue-repair research.

Sequence

Ac-LKKTETQ

This sequence uses notation outside the standard twenty one-letter codes — a lowercase letter marks a D-amino acid, and other symbols mark modified or non-standard residues. It is reproduced exactly as published rather than normalised, and no residue composition is derived from it.

Primary literature

5 peer-reviewed papers indexed in PubMed that name this compound in the title. Each record was checked against the database for title, journal and year rather than written from memory.

1. Thymosin beta-4 denotes new directions towards developing prosperous anti-aging regenerative therapies

   Int Immunopharmacol·2023·PMID 36709593

2. Thymosin beta 4 regulation of actin in sepsis

   Expert Opin Biol Ther·2018·PMID 29508629

3. Thymosin beta 4 and the eye: the journey from bench to bedside

   Expert Opin Biol Ther·2018·PMID 30063853

4. Cardioprotection by Thymosin Beta 4

   Vitam Horm·2016·PMID 27450736

5. Thymosin Beta 4 Is a Potential Regulator of Hepatic Stellate Cells

   Vitam Horm·2016·PMID 27450733

Citations are listed so the underlying research can be read directly. They describe laboratory and preclinical work on the molecule. They are not evidence of a benefit, and nothing here is an application, dose, route or outcome.

Reference databases

Links resolved against the live databases on 2026-08-29.