Tissue & Structural
BPC-157
Body Protection Compound 157
Identity
- Class
- Tissue & Structural
- Molecular weight
- 1420 Da
- Residues
- 15
- Heavy atoms
- 100
- Reference slug
- bpc-157
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
A 15-residue partial sequence derived from a protein found in human gastric juice. Studied in preclinical models for effects on connective tissue and the gastrointestinal lining. The proline-rich middle is why the backbone is modelled in a polyproline-II conformation.
Sequence
| 1 | GEPPPGKPAD DAGLV |
|---|
- Three-letter code
- Gly-Glu-Pro-Pro-Pro-Gly-Lys-Pro-Ala-Asp-Asp-Ala-Gly-Leu-Val
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. BPC-157 is built from 8 of the twenty standard amino acids across 15 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Proline | P · Pro | 4 | 26.7% |
| Glycine | G · Gly | 3 | 20% |
| Alanine | A · Ala | 2 | 13.3% |
| Aspartic acid | D · Asp | 2 | 13.3% |
| Glutamic acid | E · Glu | 1 | 6.7% |
| Lysine | K · Lys | 1 | 6.7% |
| Leucine | L · Leu | 1 | 6.7% |
| Valine | V · Val | 1 | 6.7% |
By side-chain class
Nonpolar, aliphatic
11 · 73.3%
A G L P V
Positively charged
1 · 6.7%
K
Negatively charged
3 · 20%
D E
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Primary literature
5 peer-reviewed papers indexed in PubMed that name this compound in the title. Each record was checked against the database for title, journal and year rather than written from memory.
Multifunctionality and Possible Medical Application of the BPC 157 Peptide-Literature and Patent Review
Pharmaceuticals (Basel)2025PMID 40005999
Emerging Use of BPC-157 in Orthopaedic Sports Medicine: A Systematic Review
HSS J2025PMID 40756949
Regeneration or Risk? A Narrative Review of BPC-157 for Musculoskeletal Healing
Curr Rev Musculoskelet Med2025PMID 40789979
Pentadecapeptide BPC 157 and the central nervous system
Neural Regen Res2022PMID 34380875
Stable Gastric Pentadecapeptide BPC 157 and Wound Healing
Front Pharmacol2021PMID 34267654
Citations are listed so the underlying research can be read directly. They describe laboratory and preclinical work on the molecule. They are not evidence of a benefit, and nothing here is an application, dose, route or outcome.
Reference databases
PubChem
Compound record: Bpc-157
Resolved from CAS 137525-51-0
PubMed
Indexed literature
Live search for BPC-157
ClinicalTrials.gov
Registered studies
Live search for BPC-157
Links resolved against the live databases on 2026-08-29.
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This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.