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Research Use Only·Not for human or animal consumption·21+

PepXtide

Antimicrobial

Pexiganan

Magainin 2 with more lysines

Reference entry · not stocked

18 more in Antimicrobial
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Identity

Class
Antimicrobial
Molecular weight
2477 Da
Residues
22
Heavy atoms
176
Reference slug
pexiganan

These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.

What this compound is

Magainin redesigned with extra lysines to make it more strongly cationic. Both are in the library, and comparing them shows a natural peptide next to a deliberately engineered version of itself.

Sequence

Pexiganan amino-acid sequence in one-letter code, numbered by residue position
1GIGKFLKKAK KFGKAFVKIL KK
Three-letter code
Gly-Ile-Gly-Lys-Phe-Leu-Lys-Lys-Ala-Lys-Lys-Phe-Gly-Lys-Ala-Phe-Val-Lys-Ile-Leu-Lys-Lys

The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.

Residue composition

Counted directly from the sequence above. Pexiganan is built from 7 of the twenty standard amino acids across 22 positions.

By residue

Count of each amino acid in Pexiganan
ResidueCodeCountShare
LysineK · Lys940.9%
PhenylalanineF · Phe313.6%
GlycineG · Gly313.6%
AlanineA · Ala29.1%
IsoleucineI · Ile29.1%
LeucineL · Leu29.1%
ValineV · Val14.5%

By side-chain class

  • Nonpolar, aliphatic

    10 · 45.5%

    A G I L V

  • Aromatic

    3 · 13.6%

    F

  • Positively charged

    9 · 40.9%

    K

Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.

Others in Antimicrobial

Alloferon

13 residues · 1265 Da

Thirteen residues, six of them glycine and four histidine, which makes the backbone unusually fl…

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Aurein 1.2

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Thirteen residues forming a short helix with a clear split between its charged and greasy faces.

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Bactenecin

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Twelve residues with cysteines at three and eleven joined by a disulfide, closing a loop with a…

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Beta-defensin 2

41 residues · 4328 Da

Forty-one residues with three disulfides in a different arrangement to the alpha-defensin above.…

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Buforin II

21 residues · 2435 Da

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Cecropin B

35 residues · 3835 Da

Thirty-five residues in two helices joined by a hinge: a charged one at the front and a hydropho…

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All 18 compounds in Antimicrobial

This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.