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PepXtide

Antimicrobial

Protegrin-1

Reference entry · not stocked

18 more in Antimicrobial
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Identity

Class
Antimicrobial
Molecular weight
2156 Da
Residues
18
Heavy atoms
148
Reference slug
protegrin-1

These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.

What this compound is

Eighteen residues held by two disulfides into a hairpin. Both bonds are drawn, and the chain is folded until each reaches a real bonding distance rather than having lines drawn across it.

Sequence

Protegrin-1 amino-acid sequence in one-letter code, numbered by residue position
1RGGRLCYCRR RFCVCVGR
Three-letter code
Arg-Gly-Gly-Arg-Leu-Cys-Tyr-Cys-Arg-Arg-Arg-Phe-Cys-Val-Cys-Val-Gly-Arg

The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.

Residue composition

Counted directly from the sequence above. Protegrin-1 is built from 7 of the twenty standard amino acids across 18 positions.

By residue

Count of each amino acid in Protegrin-1
ResidueCodeCountShare
ArginineR · Arg633.3%
CysteineC · Cys422.2%
GlycineG · Gly316.7%
ValineV · Val211.1%
PhenylalanineF · Phe15.6%
LeucineL · Leu15.6%
TyrosineY · Tyr15.6%

By side-chain class

  • Nonpolar, aliphatic

    6 · 33.3%

    G L V

  • Aromatic

    2 · 11.1%

    F Y

  • Polar, uncharged

    4 · 22.2%

    C

  • Positively charged

    6 · 33.3%

    R

Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.

Others in Antimicrobial

Alloferon

13 residues · 1265 Da

Thirteen residues, six of them glycine and four histidine, which makes the backbone unusually fl…

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Aurein 1.2

13 residues · 1480 Da

Thirteen residues forming a short helix with a clear split between its charged and greasy faces.

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Bactenecin

12 residues · 1484 Da

Twelve residues with cysteines at three and eleven joined by a disulfide, closing a loop with a…

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Beta-defensin 2

41 residues · 4328 Da

Forty-one residues with three disulfides in a different arrangement to the alpha-defensin above.…

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Buforin II

21 residues · 2435 Da

Twenty-one residues cut from histone H2A, the protein that packages DNA. A proline in the middle…

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Cecropin B

35 residues · 3835 Da

Thirty-five residues in two helices joined by a hinge: a charged one at the front and a hydropho…

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All 18 compounds in Antimicrobial

This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.