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PepXtide

Mitochondrial & Redox

Glutathione

Gamma-glutamyl-cysteinyl-glycine

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Identity

Class
Mitochondrial & Redox
Molecular weight
307 Da
Residues
3
Heavy atoms
36
Reference slug
glutathione

These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.

What this compound is

A tripeptide of glutamate, cysteine and glycine. One honest caveat about this model: the first bond is a gamma-glutamyl linkage from the side chain rather than the usual backbone bond, and the engine draws a standard peptide bond, so the connection point is drawn conventionally rather than exactly.

Sequence

Glutathione amino-acid sequence in one-letter code, numbered by residue position
1ECG
Three-letter code
Glu-Cys-Gly

The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.

Residue composition

Counted directly from the sequence above. Glutathione is built from 3 of the twenty standard amino acids across 3 positions.

By residue

Count of each amino acid in Glutathione
ResidueCodeCountShare
CysteineC · Cys133.3%
Glutamic acidE · Glu133.3%
GlycineG · Gly133.3%

By side-chain class

  • Nonpolar, aliphatic

    1 · 33.3%

    G

  • Polar, uncharged

    1 · 33.3%

    C

  • Negatively charged

    1 · 33.3%

    E

Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.

Primary literature

5 peer-reviewed papers indexed in PubMed that name this compound in the title. Each record was checked against the database for title, journal and year rather than written from memory.

  1. Glutathione metabolism

    Methods Enzymol1995PMID 7651209

  2. Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging

    Ageing Res Rev2023PMID 37683986

  3. Glutathione Degradation

    Antioxid Redox Signal2017PMID 28537416

  4. Glutathione and mitochondria

    Front Pharmacol2014PMID 25024695

  5. Glutathione synthesis

    Biochim Biophys Acta2013PMID 22995213

Citations are listed so the underlying research can be read directly. They describe laboratory and preclinical work on the molecule. They are not evidence of a benefit, and nothing here is an application, dose, route or outcome.

Reference databases

Links resolved against the live databases on 2026-08-29.

All 4 compounds in Mitochondrial & Redox

This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.