Mitochondrial & Redox
Glutathione
Gamma-glutamyl-cysteinyl-glycine
Identity
- Class
- Mitochondrial & Redox
- Molecular weight
- 307 Da
- Residues
- 3
- Heavy atoms
- 36
- Reference slug
- glutathione
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
A tripeptide of glutamate, cysteine and glycine. One honest caveat about this model: the first bond is a gamma-glutamyl linkage from the side chain rather than the usual backbone bond, and the engine draws a standard peptide bond, so the connection point is drawn conventionally rather than exactly.
Sequence
| 1 | ECG |
|---|
- Three-letter code
- Glu-Cys-Gly
The one-letter code gives the amino-acid backbone. Terminal modifications, where a compound carries them, are accounted for in the molecular weight above but are not visible in the letters.
Residue composition
Counted directly from the sequence above. Glutathione is built from 3 of the twenty standard amino acids across 3 positions.
By residue
| Residue | Code | Count | Share |
|---|---|---|---|
| Cysteine | C · Cys | 1 | 33.3% |
| Glutamic acid | E · Glu | 1 | 33.3% |
| Glycine | G · Gly | 1 | 33.3% |
By side-chain class
Nonpolar, aliphatic
1 · 33.3%
G
Polar, uncharged
1 · 33.3%
C
Negatively charged
1 · 33.3%
E
Side-chain classes follow the standard grouping of the twenty proteinogenic amino acids. Composition is arithmetic over the published sequence and says nothing about how the molecule behaves.
Primary literature
5 peer-reviewed papers indexed in PubMed that name this compound in the title. Each record was checked against the database for title, journal and year rather than written from memory.
Glutathione metabolism
Methods Enzymol1995PMID 7651209
Glutathione and glutathione-dependent enzymes: From biochemistry to gerontology and successful aging
Ageing Res Rev2023PMID 37683986
Glutathione Degradation
Antioxid Redox Signal2017PMID 28537416
Glutathione and mitochondria
Front Pharmacol2014PMID 25024695
Glutathione synthesis
Biochim Biophys Acta2013PMID 22995213
Citations are listed so the underlying research can be read directly. They describe laboratory and preclinical work on the molecule. They are not evidence of a benefit, and nothing here is an application, dose, route or outcome.
Reference databases
PubChem
Compound record: Glutathione
Resolved from the compound name
PubMed
Indexed literature
Live search for Glutathione
ClinicalTrials.gov
Registered studies
Live search for Glutathione
Links resolved against the live databases on 2026-08-29.
Others in Mitochondrial & Redox
MOTS-c
16 residues · 2175 Da
A 16-residue peptide encoded in mitochondrial DNA rather than the nuclear genome. Investigated i…
In our catalogue
SS-31
4 residues · 640 Da
A four-residue peptide with an alternating aromatic-cationic motif that concentrates at the inne…
In our catalogue
Humanin
24 residues · 2687 Da
Twenty-four residues encoded in mitochondrial DNA rather than the nuclear genome, like MOTS-c. A…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.