Mitochondrial & Redox
SS-31
Elamipretide - D-Arg-Dmt-Lys-Phe-NH2
Identity
- Class
- Mitochondrial & Redox
- Molecular weight
- 640 Da
- Residues
- 4
- Heavy atoms
- 97
- Reference slug
- ss-31
These are published properties of the molecule, given for identification. Values we cannot confirm are omitted rather than estimated. What these terms mean.
What this compound is
A four-residue peptide with an alternating aromatic-cationic motif that concentrates at the inner mitochondrial membrane. Studied for its interaction with cardiolipin. Residue 2 is 2,6-dimethyltyrosine, modelled with both ring methyls.
Sequence
D-Arg-Dmt-Lys-Phe-NH2
This sequence uses notation outside the standard twenty one-letter codes — a lowercase letter marks a D-amino acid, and other symbols mark modified or non-standard residues. It is reproduced exactly as published rather than normalised, and no residue composition is derived from it.
Reference databases
PubChem
Compound record: Elamipretide
Resolved from CAS 736992-21-5
PubMed
Indexed literature
Live search for SS-31
ClinicalTrials.gov
Registered studies
Live search for SS-31
Links resolved against the live databases on 2026-08-29.
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A 16-residue peptide encoded in mitochondrial DNA rather than the nuclear genome. Investigated i…
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Humanin
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Twenty-four residues encoded in mitochondrial DNA rather than the nuclear genome, like MOTS-c. A…
Reference entry
This is a reference entry. Sequence, residue count, molecular weight and atom count are published properties of the molecule, given for identification. Nothing on this page describes an application, benefit, dose, route or outcome, and nothing here should be read as an offer to supply or as guidance for use in a person or an animal. Materials sold by PepXtide are for laboratory research use only, are not for human or animal consumption, and have not been evaluated by the FDA.